The fourth edition of Lehninger Principles of Biochemistry stays true to the vision of its predecessors while embracing the advances made in biochemical research since the previous edition. As always, the book presents the fundamentals of biochemistry through selected topics, and emphasizes the most important recent developments and applications without abandoning the classical core of the subject. The new edition has been carefully streamlined to reduce the length of the book without compromizing content. As with previous editions, it emphasizes clear prose and student friendly explanations to optimize student comprehension. It also contains a groundbreaking new treatment of metabolic regulation, up to date coverage of DNA based information technologies, many new applications and problems, and a new graphical style for enzyme reaction mechanisms, including step by step annotations that clarify the concepts and chemical logic of enzymatic reactions. Lecturer supplements include: Instructor's Resource CD ROM with Test Bank, Printed Test Bank and a set of 150 Overhead Transparencies. For students a Study Guide and Solutions Manual is available which includes discussion questions, a self test and a Cellular Metabolic Map, as well as a Lecture Notebook containing the essential diagrams and reaction equations in the text. The textbook's dedicated website http://www whfreeman.com/lehninger offers numerous features including PowerPoint images, animated mechanisms and living graphs.

本书由DNA双螺旋的发现老者之一——James D.Watson及其他几位著名学者在第四版的基础上修订完成。本书除了反映分子生物学领域的最新进展之外，还涉及其他诸多方面的内容。此次修订仍保留了原书中的许多定义和特点，全书共分五篇：化学和遗传学、基因组的维持、基因组的表达、调控，以及全新内容的第五篇——方法。 本书具有权威性，内容新颖、详尽，堪称此领域的经典之作。为广大的生物爱好者及研究人员提供了分子生物学的知识框架和实验途径，并强调了基因科学对于整个生物领域的重要意义。

The publication of Darwin's The Origin of Species in 1859 marked a dramatic turning point in scientific thought.The volume had taken Darwin more than twenty years to publish, in part because he envisioned the storm of controversy it was certain to unleash. Indeed, selling out its first edition on its first day, The Origin of Species revolutionized science, philosophy, and theology.Darwin's reasoned, documented arguments carefully advance his theory of natural selection and assertion that species were not created all at once by a divine hand but started with a few simple forms that mutated and adapted over time. Whether commenting on his own ill health, discussing his experiments to test instinct in bees, or relating a conversation about a South American burrowing rodent, Darwin's monumental achievement is surprisingly personal and delightfully readable. Its ideas remain extremely profound even today, making itthe most influential book in the natural sciences ever written-a work not just important to its time, but to the history of humankind.

At last, here’s what you should’ve learned in high school biology! This paperback edition is an Everyman’s humorous look at the real differencesbiological, historical, psychologicalbetween men and womenwith fun and provocative insight into what really drives behavior and interactions between men and women. Men talk about women to men. Women talk about men to women. Men and women talk to each other (or try to) about relationships. It’s Not You, It’s Biology provides insight, ammunition, snappy comebacks, and interesting cocktail party banter for everyone who ever wondered why we do what we do vis-a-vis the opposite sex. It’s Freakonomics for the Relationship-Challenged.

In this classic, originally published 25 years ago and now reprinted with a new Afterword by the author on how he came to write the book, Judson tells the story of the birth and early development of molecular biology, in the US, the UK and France. In particular, the fascinating account of the remarkable golden period from the revelation of the double helix structure of DNA through to cracking the genetic code and solving the basic problems of how genes are regulated, is told largely in the words of the main players in the unfolding drama, all of whom were interviewed extensively by Judson in preparing this acclaimed volume. As well as the new Afterword that appears here for the first time, the current edition contains the material added by the author to the earlier "Expanded Edition" (CSHL Press 1996) on some of the principal figures involved, particularly Rosalind Franklin, together with the Afterword added at that time which sketches the further development of molecular biology into the era of recombinant DNA.