We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.

Bayesian Networks: An Introduction provides a self-contained introduction to the theory and applications of Bayesian networks, a topic of interest and importance for statisticians, computer scientists and those involved in modelling complex data sets. The material has been extensively tested in classroom teaching and assumes a basic knowledge of probability, statistics and mathematics. All notions are carefully explained and feature exercises throughout. Features include: An introduction to Dirichlet Distribution, Exponential Families and their applications. A detailed description of learning algorithms and Conditional Gaussian Distributions using Junction Tree methods. A discussion of Pearl's intervention calculus, with an introduction to the notion of see and do conditioning. All concepts are clearly defined and illustrated with examples and exercises. Solutions are provided online. This book will prove a valuable resource for postgraduate students of statistics, computer engineering, mathematics, data mining, artificial intelligence, and biology. Researchers and users of comparable modelling or statistical techniques such as neural networks will also find this book of interest.

This third edition of a classic textbook presents a comprehensive introduction to Bayesian data analysis. Written for students and researchers alike, the text is written in an easily accessible manner with chapters that contain many exercises as well as detailed worked examples taken from various disciplines. This third edition provides two new chapters on Bayesian nonparametrics and covers computation systems BUGS and R. It also offers enhanced computing advice. The book's website includes solutions to the problems, data sets, software advice, and other ancillary material.

Incorporating new and updated information, this second edition of THE bestselling text in Bayesian data analysis continues to emphasize practice over theory, describing how to conceptualize, perform, and critique statistical analyses from a Bayesian perspective. Its world-class authors provide guidance on all aspects of Bayesian data analysis and include examples of real statistical analyses, based on their own research, that demonstrate how to solve complicated problems. Changes in the new edition include: Stronger focus on MCMC Revision of the computational advice in Part III New chapters on nonlinear models and decision analysis Several additional applied examples from the authors' recent research Additional chapters on current models for Bayesian data analysis such as nonlinear models, generalized linear mixed models, and more Reorganization of chapters 6 and 7 on model checking and data collection Bayesian computation is currently at a stage where there are many reasonable ways to compute any given posterior distribution. However, the best approach is not always clear ahead of time. Reflecting this, the new edition offers a more pluralistic presentation, giving advice on performing computations from many perspectives while making clear the importance of being aware that there are different ways to implement any given iterative simulation computation. The new approach, additional examples, and updated information make Bayesian Data Analysis an excellent introductory text and a reference that working scientists will use throughout their professional life.